{"product_id":"ar-polyclonal-antibody-gcp32","title":"AR Polyclonal Antibody-GCP32","description":"\u003cp\u003eAR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: GCP32-50, GCP32-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P10275\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003cbr\u003e\nIHC: 1:50~1:200\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding. This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: AR polyclonal antibody detects endogenous levels of AR protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 140 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of AR polyclonal antibody at 1:2000 dilution\u003cbr\u003e\n Lane 1: CT-26 whole cell lysate (40ug)\u003cbr\u003e\n Lane 2: PC3 whole cell lysate (40ug)\u003cbr\u003e\n Lane 3: HepG2 whole cell lysate (40ug), Immunofluorescence analysis of PC3 cells using AR antibody at dilution of 1:50., Immunohistochemistry of paraffin-embedded Rat Brain using AR antibody at dilution of 1:50.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human AR.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993768005811,"sku":"GCP32-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993768038579,"sku":"GCP32-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a07493b6-127b-4602-8c70-15a0745ec279.jpg?v=1706183323","url":"https:\/\/afsbio.com\/products\/ar-polyclonal-antibody-gcp32","provider":"AFSBio Inc.","version":"1.0","type":"link"}