{"product_id":"arhgap15-polyclonal-antibody-e-ab-14604","title":"ARHGAP15 Polyclonal Antibody - E-AB-14604","description":"\u003cp\u003eARHGAP15 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-14604-60, E-AB-14604-120, E-AB-14604-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ARHGAP15\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ArhGAP15; BM046; RHG15; Rho GTPase activating protein 15; Rho GTPase-activating protein 15; Rho type GTPase activating protein 15; Rho-type GTPase-activating protein 15\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q53QZ3\u003c\/p\u003e\n\n\u003cp\u003eBackground: RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]). GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ARHGAP15\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124156170419,"sku":"E-AB-14604-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124156203187,"sku":"E-AB-14604-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124156235955,"sku":"E-AB-14604-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_eab86eba-b0ec-415d-9767-1955aae742c3.png?v=1709724891","url":"https:\/\/afsbio.com\/products\/arhgap15-polyclonal-antibody-e-ab-14604","provider":"AFSBio Inc.","version":"1.0","type":"link"}