{"product_id":"arhgef10-polyclonal-antibody-e-ab-10831","title":"ARHGEF10 Polyclonal Antibody - E-AB-10831","description":"\u003cp\u003eARHGEF10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10831-60, E-AB-10831-120, E-AB-10831-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ARHGEF10\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ARHGA; ARHGEF10; DKFZp686H0726; GEF10; KIAA0294; MGC131664; Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O15013\u003c\/p\u003e\n\n\u003cp\u003eBackground: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1, 369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ARHGEF10\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136092864691,"sku":"E-AB-10831-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136092897459,"sku":"E-AB-10831-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136092930227,"sku":"E-AB-10831-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5c90412f-58ad-45ff-9270-75444dd1a1d3.png?v=1709987755","url":"https:\/\/afsbio.com\/products\/arhgef10-polyclonal-antibody-e-ab-10831","provider":"AFSBio Inc.","version":"1.0","type":"link"}