{"product_id":"arhgef12-polyclonal-antibody-bs65299","title":"ARHGEF12 Polyclonal Antibody-BS65299","description":"\u003cp\u003eARHGEF12 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65299-50, BS65299-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9NZN5\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Rho guanine nucleotide exchange factor 12(ARHGEF12) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid\/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: LARG Polyclonal Antibody detects endogenous levels of LARG protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 173 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot analysis of RAW264.7 cells using LARG Polyclonal Antibody, Western blot analysis of lysates from RAW264.7 cells, using ARHGEF12 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from HUVECcells using ARHGEF12 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993775607987,"sku":"BS65299-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993775640755,"sku":"BS65299-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_81e446a7-9065-4aa1-bead-9c434bd4121b.jpg?v=1706183428","url":"https:\/\/afsbio.com\/products\/arhgef12-polyclonal-antibody-bs65299","provider":"AFSBio Inc.","version":"1.0","type":"link"}