{"product_id":"arid2-rabbit-polyclonal-antibody-es18258","title":"ARID2 Rabbit Polyclonal Antibody - ES18258","description":"\u003cp\u003eARID2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18258-50, ES18258-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180, MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ARID2 AA range: 309-359\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ARID2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of ARID2 at Human\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Highly expressed in heart,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 202kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Hepatocellular carcinoma\u003c\/p\u003e\n\n\u003cp\u003eFunction: Developmental Stage: Up-regulated in adult heart (at protein level)\u003cbr\u003e\nFunction: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI\/SNF chromatin remodeling complex SWI\/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes\u003cbr\u003e\nSequence Caution: Differs from position 1094 onward for unknown reason\u003cbr\u003e\nSimilarity: Contains 1 ARID domain\u003cbr\u003e\nSimilarity: Contains 1 C2H2-type zinc finger\u003cbr\u003e\nSubunit: Component of the SWI\/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4\/BRG1, SMARCB1\/BAF47, ACTL6A\/BAF53A or ACTL6B\/BAF53B, SMARCE1\/BAF57, SMARCD1\/BAF60A, SMARCD2\/BAF60B, perhaps SMARCD3\/BAF60C, SMARCC1\/BAF155, SMARCC2\/BAF170, PB1\/BAF180, ARID2\/BAF200, ARID1A\/BAF250A or ARID1B\/BAF2\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ARID2 KIAA1557\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: ARID2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315781718195,"sku":"ES18258-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315781750963,"sku":"ES18258-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/arid2-rabbit-polyclonal-antibody-es18258","provider":"AFSBio Inc.","version":"1.0","type":"link"}