{"product_id":"asb8-polyclonal-antibody-e-ab-10961","title":"ASB8 Polyclonal Antibody - E-AB-10961","description":"\u003cp\u003eASB8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10961-60, E-AB-10961-120, E-AB-10961-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ASB8\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Ankyrin repeat and SOCS box containing 8; Ankyrin repeat and SOCS box protein 8; ASB 8; ASB-8; ASB8; ASB8; FLJ21255; MGC5540; OTTHUMP00000237000; OTTHUMP00000237001; OTTHUMP00000237007; OTTHUMP00000237009; OTTHUMP00000237010; PP14212\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9H765\u003c\/p\u003e\n\n\u003cp\u003eBackground: ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.7 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human ASB8\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124064714931,"sku":"E-AB-10961-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124064747699,"sku":"E-AB-10961-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124064780467,"sku":"E-AB-10961-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3f65a6c7-7a14-4055-aa96-4f5883e66dee.png?v=1709723271","url":"https:\/\/afsbio.com\/products\/asb8-polyclonal-antibody-e-ab-10961","provider":"AFSBio Inc.","version":"1.0","type":"link"}