{"product_id":"ascl1-polyclonal-antibody-ra22130","title":"ASCL1 Polyclonal Antibody - RA22130","description":"ASCL1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA22130-50, RA22130-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: ASCL1; ASH1; BHLHA46; HASH1; Achaete-scute homolog 1; ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 429\n\nProtein MW (KDa): 25\n\nSWISS: P50553\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121098219699,"sku":"RA22130-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121098252467,"sku":"RA22130-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e11ac436-1669-45fe-ae0f-ca5a4891262d.png?v=1773371011","url":"https:\/\/afsbio.com\/products\/ascl1-polyclonal-antibody-ra22130","provider":"AFSBio Inc.","version":"1.0","type":"link"}