{"product_id":"aspp1-polyclonal-antibody-bt-ap14348","title":"ASPP1 Polyclonal Antibody - BT-AP14348","description":"\u003cp\u003eASPP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14348-20, BT-AP14348-50, BT-AP14348-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PPP1R13B\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Apoptosis-stimulating of p53 protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96KQ4; Mouse: Q62415\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Apoptosis-stimulating of p53 protein 1;Protein phosphatase 1 regulatory subunit 13B; Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23368; Mouse: 21981\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239057449139,"sku":"BT-AP14348-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239057481907,"sku":"BT-AP14348-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239057514675,"sku":"BT-AP14348-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_44207915-6dc7-4a4f-8291-265aaf329f1d.png?v=1769388517","url":"https:\/\/afsbio.com\/products\/aspp1-polyclonal-antibody-bt-ap14348","provider":"AFSBio Inc.","version":"1.0","type":"link"}