{"product_id":"atf2-monoclonal-antibody-bt-mca2473","title":"ATF2 Monoclonal Antibody - BT-MCA2473","description":"\u003cp\u003eATF2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2473-50, BT-MCA2473-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATF2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4F12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ATF2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ATF2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P15336\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1386\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238605709491,"sku":"BT-MCA2473-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238605742259,"sku":"BT-MCA2473-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b76f6d02-175b-4f4f-8713-c49753467f6a.png?v=1769382993","url":"https:\/\/afsbio.com\/products\/atf2-monoclonal-antibody-bt-mca2473","provider":"AFSBio Inc.","version":"1.0","type":"link"}