{"product_id":"atf6b-s425-polyclonal-antibody-bs2131","title":"ATF6B (S425) Polyclonal Antibody-BS2131","description":"\u003cp\u003eATF6B (S425) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2131-50, BS2131-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q99941\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α\/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α\/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ATF6B (S425) polyclonal antibody detects endogenous levels of ATF6B protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ATF6B pAb at 1:500 dilution\u003cbr\u003e\nLane1:The Embryo tissue lysate of Mouse(40ug)\u003cbr\u003e\nLane2:C6 whole cell lysate(40ug)\u003cbr\u003e\nLane3:CT-26 whole cell lysate(40ug)\u003cbr\u003e\nLane4:HEK293T whole cell lysate (40ug) \u003cbr\u003e\nLane5:DLD whole cell lysate(40ug)    \u003cbr\u003e\nLane6:A2780 whole cell lysate(40ug)\u003c\/p\u003e    \n\n\u003cp\u003eBioworld Molecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta; ATF6B; CREBL1; G13; ATF-6β; ATF6β\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910468145331,"sku":"BS2131-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910468178099,"sku":"BS2131-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f498ea7e-2e4f-42ac-b16d-30f8a9111e86.jpg?v=1703092984","url":"https:\/\/afsbio.com\/products\/atf6b-s425-polyclonal-antibody-bs2131","provider":"AFSBio Inc.","version":"1.0","type":"link"}