{"product_id":"atg13-rabbit-pab-es20862","title":"ATG13 Rabbit pAb - ES20862","description":"\u003cp\u003eATG13 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20862-50, ES20862-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1\/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: Autophagy-related protein 13\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p 1:50-200, WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ATG13 AA range: 182-232\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 72kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9776\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O75143\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202438193331,"sku":"ES20862-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202438226099,"sku":"ES20862-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_4064eee0-7d98-4c5f-be75-2d4ee0e7f640.png?v=1767129171","url":"https:\/\/afsbio.com\/products\/atg13-rabbit-pab-es20862","provider":"AFSBio Inc.","version":"1.0","type":"link"}