{"product_id":"atg4d-polyclonal-antibody-bs70951","title":"ATG4D Polyclonal Antibody-BS70951","description":"\u003cp\u003eATG4D Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS70951-50, BS70951-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q86TL0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ATG4D polyclonal antibody detects endogenous levels of ATG4D protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 53 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot (WB) analysis of ATG4D pAb at 1:1000 dilution\u003cbr\u003e\n Lane1:The Lung tissue lysate of Mouse(40ug)\u003cbr\u003e\n Lane2:The Lung tissue lysate of Rat(40ug)\u003cbr\u003e\n Lane3:H1792 whole cell lysate(40ug)\u003cbr\u003e\n Lane4:SGC7901 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: APG4D; AUTL4; APG4-D;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombination protein, corresponding to amino acids 123-474 of Human ATG4D.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923493064883,"sku":"BS70951-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923493097651,"sku":"BS70951-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_727e3bbb-62a7-4f60-9446-308c7140bae4.jpg?v=1703850452","url":"https:\/\/afsbio.com\/products\/atg4d-polyclonal-antibody-bs70951","provider":"AFSBio Inc.","version":"1.0","type":"link"}