{"product_id":"atg5-3c7-mouse-mab-em1374","title":"ATG5 (3C7) Mouse mAb - EM1374","description":"\u003cp\u003eATG5 (3C7) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1374-50, EM1374-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: APG5, APG5L, ASP, Autophagy protein 5 antibody\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB  1:5, 000-10, 000 IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 55kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9494\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9H1Y0\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm,  Membrane\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201995923635,"sku":"EM1374-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201995956403,"sku":"EM1374-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_0990f7fc-2eb9-4231-ba37-2277695832bc.png?v=1767119577","url":"https:\/\/afsbio.com\/products\/atg5-3c7-mouse-mab-em1374","provider":"AFSBio Inc.","version":"1.0","type":"link"}