{"product_id":"atm-9f7-monoclonal-antibody-mb3299","title":"ATM (9F7) Monoclonal Antibody-MB3299","description":"\u003cp\u003eATM (9F7) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3299-50, MB3299-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13315\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the PI3\/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: -\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using ATM antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using ATM antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide conjugated to KLH.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970468679859,"sku":"MB3299-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970468712627,"sku":"MB3299-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_833ac7fc-3fba-4b07-b569-6777e0bd02ea.jpg?v=1705525746","url":"https:\/\/afsbio.com\/products\/atm-9f7-monoclonal-antibody-mb3299","provider":"AFSBio Inc.","version":"1.0","type":"link"}