{"product_id":"atp1a1-phospho-s23-polyclonal-antibody-bs64292","title":"ATP1A1 (phospho-S23) Polyclonal Antibody - BS64292","description":"\u003cp\u003eATP1A1 (phospho-S23) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS64292-50, BS64292-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ubiquitously expressed sodium\/potassium-ATPase (Na+\/K+-ATPase) exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecμle of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+\/K+-ATPase plays a critical role in maintaining cellμlar volume, resting membrane potential and Na+-coupled solute transport. Mμltiple isoforms of three subunits, α, β and γ, comprise to form the Na+\/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations, the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+\/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+\/K+-ATPase.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Sodium\/potassium-transporting ATPase subunit alpha-1, Na(+)\/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1, ATP1A1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human ATP1A1 around the phosphorylation site of Serine23.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: p-ATP1A1(S23) polyclonal antibody detects endogenous levels of ATP1A1 protein only when phosphorylated at Ser23 .\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 100 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P05023\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1 mg\/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938482839731,"sku":"BS64292-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938482872499,"sku":"BS64292-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/atp1a1-phospho-s23-polyclonal-antibody-bs64292","provider":"AFSBio Inc.","version":"1.0","type":"link"}