{"product_id":"atp1a2-polyclonal-antibody-bs3401","title":"ATP1A2 Polyclonal Antibody-BS3401","description":"\u003cp\u003eATP1A2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3401-50, BS3401-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P50993\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ubiquitously expressed sodium\/potassium-ATPase (Na+\/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+\/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+\/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+\/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+\/K+-ATPase.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ATP1A2 polyclonal antibody detects endogenous levels of ATP1A2 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ATP1A2 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane1:Hela whole cell lysate(40ug)\u003cbr\u003e\nLane2:H1792 whole cell lysate(40ug)\u003cbr\u003e\nLane3:Panc1 whole cell lysate(40ug)\u003cbr\u003e\nLane4:Aml-12 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 95kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Sodium\/potassium-transporting ATPase subunit alpha-2;Na(+)\/K(+) ATPase alpha-2 subunit;Sodium pump subunit alpha-2;ATP1A2;KIAA0778;\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human ATP1A2 .\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910466769075,"sku":"BS3401-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910466801843,"sku":"BS3401-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_52b1da25-4935-4703-b477-053009ab35cd.jpg?v=1703092953","url":"https:\/\/afsbio.com\/products\/atp1a2-polyclonal-antibody-bs3401","provider":"AFSBio Inc.","version":"1.0","type":"link"}