{"product_id":"atp6-polyclonal-antibody-bs1681","title":"ATP6 Polyclonal Antibody-BS1681","description":"\u003cp\u003eATP6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1681-50, BS1681-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P00848\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground:  ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS),Leber hereditary optic neuropathy(LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ATP6 polyclonal antibody detects endogenous levels of ATP6 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ATP6 polyclonal antibody at 1:1000 dilution\u003cbr\u003e\nLane1:The muscle tissue lysate of Rat (47μg)\u003cbr\u003e\nLane2:The muscle tissue lysate of Mouse(37μg)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ATP synthase subunit a; F-ATPase protein 6; Mtatp6; Atp6; Atpase6; mt-Atp6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910475780275,"sku":"BS1681-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910475813043,"sku":"BS1681-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a84cd5af-4873-4f3a-b93e-e1a0ed735839.jpg?v=1703093168","url":"https:\/\/afsbio.com\/products\/atp6-polyclonal-antibody-bs1681","provider":"AFSBio Inc.","version":"1.0","type":"link"}