{"product_id":"atp6v0a4-monoclonal-antibody-bt-mca2796","title":"ATP6V0A4 Monoclonal Antibody - BT-MCA2796","description":"\u003cp\u003eATP6V0A4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2796-50, BT-MCA2796-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATP6V0A4\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 9C9H9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ATP6V0A4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human ATP6V0A4 (AA: 228-390) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 96.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9HBG4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: A4, STV1, VPH1, VPP2, DRTA3, RTA1C, RTADR, ATP6N2, RDRTA2, ATP6N1B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 50617\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238519398579,"sku":"BT-MCA2796-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238519431347,"sku":"BT-MCA2796-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2008461c-a43d-4294-bfcf-d34b6fe014e9.png?v=1769382075","url":"https:\/\/afsbio.com\/products\/atp6v0a4-monoclonal-antibody-bt-mca2796","provider":"AFSBio Inc.","version":"1.0","type":"link"}