{"product_id":"ats3-rabbit-polyclonal-antibody-es18187","title":"ATS3 Rabbit Polyclonal Antibody - ES18187","description":"\u003cp\u003eATS3 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18187-50, ES18187-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ATS3 AA range: 600-650\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ATS3\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of ATS3 at Human\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Found in cartilage and skin,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 133kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Caution: Has sometimes been referred to as ADAMTS4\u003cbr\u003e\nCofactor: Binds 1 zinc ion per subunit\u003cbr\u003e\nDomain: The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular matrix\u003cbr\u003e\nFunction: Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens\u003cbr\u003e\nPTM: The precursor is cleaved by a furin endopeptidase\u003cbr\u003e\nSimilarity: Contains 1 disintegrin domain\u003cbr\u003e\nSimilarity: Contains 1 peptidase M12B domain\u003cbr\u003e\nSimilarity: Contains 1 PLAC domain\u003cbr\u003e\nSimilarity: Contains 4 TSP type-1 domains\u003cbr\u003e\nTissue Specificity: Found in cartilage and skin\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Secreted Secreted, extracellular space, extracellular matrix\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ADAMTS3 KIAA0366\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: ATS3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315764121779,"sku":"ES18187-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315764154547,"sku":"ES18187-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/ats3-rabbit-polyclonal-antibody-es18187","provider":"AFSBio Inc.","version":"1.0","type":"link"}