{"product_id":"ats5-polyclonal-antibody-ra31227","title":"ATS5 Polyclonal Antibody - RA31227","description":"\u003cp\u003eATS5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA31227-50, RA31227-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 11096\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 102\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UNA0\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120425885875,"sku":"RA31227-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120425918643,"sku":"RA31227-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9c11ea5e-a729-43b9-8cfa-79a2e66e2ab2.png?v=1773365266","url":"https:\/\/afsbio.com\/products\/ats5-polyclonal-antibody-ra31227","provider":"AFSBio Inc.","version":"1.0","type":"link"}