{"product_id":"aurora-a-polyclonal-antibody-bs90112","title":"Aurora A Polyclonal Antibody-BS90112","description":"\u003cp\u003eAurora A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90112-50, BS90112-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O14965(Human) P97477(Mouse)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003cbr\u003e\nFC:1:50-1:100\u003cbr\u003e\nICC:1:100-1:500\u003c\/p\u003e\n\n\u003cp\u003eBackground: Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2\/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Aurora A polyclonal antibody detects endogenous levels of Aurora A protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 46 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: ICC staining Aurora A in SKOV-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS., ICC staining Aurora A in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ARK-1, Aurora-related kinase 1, hARK1, AURKA, AIK, ARK-1, ARK1, AURA, Aurka, Aurora 2, Aurora A, Aurora kinase A, Aurora-related kinase 1, Aurora\/IPL1 like kinase, Aurora\/IPL1-related kinase 1, AURORA2, Breast tumor-amplified kinase, BTAK, hARK1, IAK, IPL1 related kinase, MGC34538, OTTHUMP00000031340, OTTHUMP00000031341, OTTHUMP00000031342, OTTHUMP00000031343, OTTHUMP00000031344, OTTHUMP00000031345, OTTHUMP00000166071, OTTHUMP00000166072, PPP1R47, Protein phosphatase 1, regulatory subunit 47, Serine\/threonine kinase 15, Serine\/threonine kinase 6, Serine\/threonine-protein kinase 15, Serine\/threonine-protein kinase 6, Serine\/threonine-protein kinase aurora-A, STK15, STK6, STK6, STK7,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979762602163,"sku":"BS90112-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979762634931,"sku":"BS90112-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2dd7fa08-1854-4274-9e59-59225bb12c2d.jpg?v=1705748851","url":"https:\/\/afsbio.com\/products\/aurora-a-polyclonal-antibody-bs90112","provider":"AFSBio Inc.","version":"1.0","type":"link"}