{"product_id":"b2l10-polyclonal-antibody-bt-ap06629","title":"B2L10 Polyclonal Antibody - BT-AP06629","description":"\u003cp\u003eB2L10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06629-20, BT-AP06629-50, BT-AP06629-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1\/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Cancer; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BCL2L10\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bcl-2-like protein 10\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9HD36; Mouse: Q9Z0F3; Rat: Q99M66\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Bcl-2-like protein 10;Bcl2-L-10;Anti-apoptotic protein NrH;Apoptosis regulator Bcl-B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10017\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239062102195,"sku":"BT-AP06629-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239062134963,"sku":"BT-AP06629-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239062167731,"sku":"BT-AP06629-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_aa94b4df-c832-480e-83c1-19cadf12cb86.png?v=1769388594","url":"https:\/\/afsbio.com\/products\/b2l10-polyclonal-antibody-bt-ap06629","provider":"AFSBio Inc.","version":"1.0","type":"link"}