{"product_id":"b7-h3-cd276-polyclonal-antibody-e-ab-64054","title":"B7-H3\/CD276 Polyclonal Antibody - E-AB-64054","description":"\u003cp\u003eB7-H3\/CD276 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64054-60, E-AB-64054-120, E-AB-64054-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: B7-H3\/CD276\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD276; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q5ZPR3\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human B7-H3\/CD276 (NP_001019907.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33kDa\/52kDa\/57kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 115kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146311303347,"sku":"E-AB-64054-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146311336115,"sku":"E-AB-64054-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146311368883,"sku":"E-AB-64054-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_440543a6-6e91-47a0-b438-640b28456e70.png?v=1710293415","url":"https:\/\/afsbio.com\/products\/b7-h3-cd276-polyclonal-antibody-e-ab-64054","provider":"AFSBio Inc.","version":"1.0","type":"link"}