{"product_id":"b7-h3-cd276-polyclonal-antibody-e-ab-68332","title":"B7-H3\/CD276 Polyclonal Antibody - E-AB-68332","description":"B7-H3\/CD276 Polyclonal Antibody\n\nSizes: 60μL, 120μL, 200μL\n\nCatalogue Numbers: E-AB-68332-60, E-AB-68332-120, E-AB-68332-200\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: B7-H3\/CD276\n\nTarget Synonym: CD276; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2\n\nResearch Areas: Cancer, Immunology, Stem Cells\n\nConjugation: Unconjugated\n\nHost: Rabbit\n\nSpecies Reactivity: Human\n\nApplication: WB, IHC\n\nIsotype: IgG\n\nClonality: Polyclonal\n\n \n\nUNIProt ID: Q5ZPR3\n\nBackground: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\n\nConcentration: 1 mg\/mL\n\nImmunogen: A synthetic peptide of human B7-H3\/CD276\n\nBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\n\nPurification Method: Affinity purification\n\nDilution: WB 1:500-1:2000, IHC 1:50-1:200\n\nCalculated MW: 33kDa\/52kDa\/57kDa\n\nObserved MW: 120kDa\n\nStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\n\nShipping: Ice bag\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146483400883,"sku":"E-AB-68332-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146483433651,"sku":"E-AB-68332-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146483466419,"sku":"E-AB-68332-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_546bb3bb-9295-4495-a263-bff9d1134139.png?v=1710296281","url":"https:\/\/afsbio.com\/products\/b7-h3-cd276-polyclonal-antibody-e-ab-68332","provider":"AFSBio Inc.","version":"1.0","type":"link"}