{"product_id":"bad-monoclonal-antibody-bt-mca3850","title":"BAD Monoclonal Antibody - BT-MCA3850","description":"\u003cp\u003eBAD Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3850-50, BT-MCA3850-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BAD\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1G5B3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BAD\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 18.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q92934\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BBC2, BCL2L8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 572\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238567141555,"sku":"BT-MCA3850-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238567174323,"sku":"BT-MCA3850-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7c4bb08-0af6-4316-846d-c96a73b18d1e.png?v=1769382649","url":"https:\/\/afsbio.com\/products\/bad-monoclonal-antibody-bt-mca3850","provider":"AFSBio Inc.","version":"1.0","type":"link"}