{"product_id":"baf57-polyclonal-antibody-bs90116","title":"BAF57 Polyclonal Antibody-BS90116","description":"\u003cp\u003eBAF57 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90116-50, BS90116-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q969G3(Human) O54941(Mouse) Q56A18(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC IF, IHC, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003cbr\u003e\nICC\/IF:1:50-1:200\u003cbr\u003e\nIHC:1:50-1:200\u003cbr\u003e\nIP:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The SWI\/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2α) and Brg-1 (also designated SNF2 or SNF2β) are the ATPase subunits of the mammalian SWI\/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI\/SNF complex. In higher eukaryotes, BAF57 is also a critical component of the SWI\/ SNF complex. BAF57 contains a high-mobility-group (HMG) domain adjacent to a kinesin-like region and is a DNA-binding subunit of the SWI\/SNF complex. The human BAF57 gene maps within the q12-25 region of chromosome 17, a gene-rich area implicated in breast and ovarian cancers.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: BAF57 polyclonal antibody detects endogenous levels of BAF57 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 47 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of BAF57 on SH-SY-5Y cell lysate using anti-BAF57 antibody at 1\/1,000 dilution., ICC staining BAF57 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BAF57, SMARCE1, BAF57, BRG1 associated factor 57, BRG1-associated factor 57, Chromatin remodeling complex BRG1 associated factor 57, FLJ35648, SMARCE 1, SMARCE1, SMCE1, SWI\/SNF related matrix associated actin dependent regulator of chromatin e1, SWI\/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1, SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein within human BAF57 aa 1-200.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979762798771,"sku":"BS90116-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979762831539,"sku":"BS90116-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4130273c-3e6a-4448-ad26-2b88c74d7657.jpg?v=1705748858","url":"https:\/\/afsbio.com\/products\/baf57-polyclonal-antibody-bs90116","provider":"AFSBio Inc.","version":"1.0","type":"link"}