{"product_id":"bag-1-polyclonal-antibody-bt-ap00816","title":"Bag-1 Polyclonal Antibody - BT-AP00816","description":"\u003cp\u003eBag-1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00816-20, BT-AP00816-50, BT-AP00816-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BAG1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bag-1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 38878\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q99933; Mouse: Q60739\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 573\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240132272307,"sku":"BT-AP00816-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240132305075,"sku":"BT-AP00816-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240132337843,"sku":"BT-AP00816-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_bfe7f39a-1d55-41c7-89ee-e0b20e80c562.png?v=1769403934","url":"https:\/\/afsbio.com\/products\/bag-1-polyclonal-antibody-bt-ap00816","provider":"AFSBio Inc.","version":"1.0","type":"link"}