{"product_id":"bag3-polyclonal-antibody-e-ab-40660","title":"BAG3 Polyclonal Antibody - E-AB-40660","description":"\u003cp\u003eBAG3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-40660-50, E-AB-40660-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BAG3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BAG family molecular chaperone regulator 3 ; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cell Biology,Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O95817\u003c\/p\u003e\n\n\u003cp\u003eBackground: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client\/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8\/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8\/HSC70.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Human BAG3 protein expressed by E.coli\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB:1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 62 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149048086707,"sku":"E-AB-40660-50","price":175.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149048119475,"sku":"E-AB-40660-100","price":322.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d443b4a9-04cf-4328-ab6f-aa8d2869ca7e.png?v=1710339233","url":"https:\/\/afsbio.com\/products\/bag3-polyclonal-antibody-e-ab-40660","provider":"AFSBio Inc.","version":"1.0","type":"link"}