{"product_id":"bak1-polyclonal-antibody-e-ab-70192","title":"BAK1 Polyclonal Antibody - E-AB-70192","description":"\u003cp\u003eBAK1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70192-60, E-AB-70192-120, E-AB-70192-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BAK1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Apoptosis regulator BAK; BAK; BAK like; Bak NT; BAK; Bak1; Bcl 2 homologous antagonist\/killer; Bcl 2 like 7 protein; Bcl-2 homologous antagonist\/killer; Bcl-2-like protein 7; BCL2 antagonist\/killer 1; Bcl2 like 7 Protein; Bcl2-L-7; BCL2L7; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q16611,O08734\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 3.1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthetic peptide corresponding to Mouse BAK\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 25kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146512498867,"sku":"E-AB-70192-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146512564403,"sku":"E-AB-70192-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146512597171,"sku":"E-AB-70192-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a9dc45ee-f3a4-41f7-bb6b-1a31ea824b14.png?v=1710296655","url":"https:\/\/afsbio.com\/products\/bak1-polyclonal-antibody-e-ab-70192","provider":"AFSBio Inc.","version":"1.0","type":"link"}