{"product_id":"bam32-phospho-tyr139-rabbit-pab-es5538","title":"BAM32 (phospho Tyr139) rabbit pAb - ES5538","description":"\u003cp\u003eBAM32 (phospho Tyr139) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5538-50, ES5538-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K., induction:Upon B-cell activation., PTM:Phosphorylated on tyrosine residues., similarity:Contains 1 PH domain., similarity:Contains 1 SH2 domain., subcellular location:Membrane-associated after cell stimulation leading to its translocation., subunit:Interacts with PtdIns (3, 4, 5)P3 and PLCG2. In vitro, interacts with PtdIns (3, 4)P2., tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 32kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 27071\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UN19\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202252398771,"sku":"ES5538-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202252431539,"sku":"ES5538-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_741dfa8c-9f96-4ce4-94b9-d74fb3ed1f44.png?v=1767125174","url":"https:\/\/afsbio.com\/products\/bam32-phospho-tyr139-rabbit-pab-es5538","provider":"AFSBio Inc.","version":"1.0","type":"link"}