{"product_id":"bap1-phospho-ser592-rabbit-polyclonal-antibody-ra22316","title":"BAP1 (phospho-Ser592) Rabbit Polyclonal Antibody - RA22316","description":"\u003cp\u003eBAP1 (phospho-Ser592) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22316-50, RA22316-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: BRCA1 associated protein 1 (BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 80\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight (kDa): 80\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8314\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q92560\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45121106706611,"sku":"RA22316-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121106739379,"sku":"RA22316-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product2.png?v=1787773941","url":"https:\/\/afsbio.com\/products\/bap1-phospho-ser592-rabbit-polyclonal-antibody-ra22316","provider":"AFSBio Inc.","version":"1.0","type":"link"}