{"product_id":"bbc3-polyclonal-antibody-e-ab-67059","title":"BBC3 Polyclonal Antibody - E-AB-67059","description":"\u003cp\u003eBBC3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67059-60, E-AB-67059-120, E-AB-67059-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: BBC3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BBC3; JFY-1; JFY1; PUMA\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q96PG8,Q9BXH1\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human BBC3 (NP_001120713.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 10kDa\/14kDa\/20kDa\/26kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148679708851,"sku":"E-AB-67059-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148679741619,"sku":"E-AB-67059-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148679774387,"sku":"E-AB-67059-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a2464774-d407-4c43-a383-a7d57bc44408.png?v=1710327945","url":"https:\/\/afsbio.com\/products\/bbc3-polyclonal-antibody-e-ab-67059","provider":"AFSBio Inc.","version":"1.0","type":"link"}