{"product_id":"bcl-2-rabbit-pab-a25052","title":"Bcl-2 Rabbit pAb - A25052","description":"\u003cp\u003eBcl-2 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25052-20, A25052-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables BH domain binding activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Located in cytosol; mitochondrial crista; and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple) ; end stage renal disease; gastric ulcer; intestinal disease (multiple) ; and status epilepticus. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; brain disease (multiple) ; hypertension (multiple) ; intrinsic cardiomyopathy (multiple) ; and neurodegenerative disease (multiple) . Human ortholog (s) of this gene implicated in several diseases, including carcinoma (multiple) ; hematologic cancer (multiple) ; intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator) .\u003c\/p\u003e \n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 26kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 26kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 24224\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P49950\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Bcl-2,\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:5000 IP, 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Apoptosis regulation, Autophagy signal transduction, Ddeath receptor signal transduction.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Bcl-2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189864030387,"sku":"A25052-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189864063155,"sku":"A25052-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_92ece5bb-0fb4-41ce-a6c9-166cfca6f6af.png?v=1766437011","url":"https:\/\/afsbio.com\/products\/bcl-2-rabbit-pab-a25052","provider":"AFSBio Inc.","version":"1.0","type":"link"}