{"product_id":"bcl-7a-n62-polyclonal-antibody-bs9274","title":"Bcl-7a (N62) Polyclonal Antibody-BS9274","description":"\u003cp\u003eBcl-7a (N62) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS9274-50, BS9274-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q4VC05\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bcl-7a (B-cell CLL\/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL). Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and\/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Bcl-7a (N62) polyclonal antibody detects endogenous levels of Bcl-7a protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of BCL7A pAb at 1:500 dilution\u003cbr\u003e\nLane1:The Fallopian tube tissue lysate of Rat(40ug)\u003cbr\u003e\nLane2:The Embryo tissue lysate of Mouse(40ug)\u003cbr\u003e\nLane3:PC12 whole cell lysate(40ug)\u003cbr\u003e\nLane4:CT-26 whole cell lysate (40ug)                                 \u003cbr\u003e\nLane5:PC3 whole cell lysate(40ug)\u003cbr\u003e\nLane6:A2780 whole cell lysate(40ug)                                   \u003cbr\u003e\nLane7:LOVO whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: B cell CLL\/lymphoma 7; B cell CLL\/lymphoma 7 protein family member A; B cell CLL\/lymphoma 7A; B-cell CLL\/lymphoma 7 protein family member A; BCL 7; BCL7; bcl7a; BCL7A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910468604083,"sku":"BS9274-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910468636851,"sku":"BS9274-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c00d86ec-6ac5-4868-a1a8-ef548b208a00.jpg?v=1703092997","url":"https:\/\/afsbio.com\/products\/bcl-7a-n62-polyclonal-antibody-bs9274","provider":"AFSBio Inc.","version":"1.0","type":"link"}