{"product_id":"bcl-7a-polyclonal-antibody-bt-ap00869","title":"Bcl-7a Polyclonal Antibody - BT-AP00869","description":"\u003cp\u003eBcl-7a Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00869-20, BT-AP00869-50, BT-AP00869-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for BCL7A.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BCL7A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Bcl-7a Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 22810\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q4VC05; Mouse: Q9CXE2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BCL7A; B-cell CLL\/lymphoma 7 protein family member A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 605; Mouse: 77045\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240136335539,"sku":"BT-AP00869-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240136368307,"sku":"BT-AP00869-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240136401075,"sku":"BT-AP00869-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ee309bb6-81d5-43bb-91da-65622c3f3fcb.png?v=1769403996","url":"https:\/\/afsbio.com\/products\/bcl-7a-polyclonal-antibody-bt-ap00869","provider":"AFSBio Inc.","version":"1.0","type":"link"}