{"product_id":"bcl-xl-polyclonal-antibody-ra22359","title":"Bcl-Xl Polyclonal Antibody - RA22359","description":"\u003cp\u003eBcl-Xl Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA22359-50, RA22359-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: BCL2 like 1 (BCL2L1) Homo sapiens The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF (paraffin section)\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Bcl-2-like protein 1 (Bcl2-L-1;Apoptosis regulator Bcl-X)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 30\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight (kDa): 30\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 598\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q07817\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45121108213939,"sku":"RA22359-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121108246707,"sku":"RA22359-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product2.png?v=1787773941","url":"https:\/\/afsbio.com\/products\/bcl-xl-polyclonal-antibody-ra22359","provider":"AFSBio Inc.","version":"1.0","type":"link"}