{"product_id":"bcl6-monoclonal-antibody-bt-mca3632","title":"BCL6 Monoclonal Antibody - BT-MCA3632","description":"\u003cp\u003eBCL6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3632-50, BT-MCA3632-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BCL6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7A6D1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BCL6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human BCL6 (AA: 507-706) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 78.8KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P41182\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 604\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238521102515,"sku":"BT-MCA3632-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238521135283,"sku":"BT-MCA3632-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f4d321bd-97a4-48f9-8c09-0bf406da5928.png?v=1769382116","url":"https:\/\/afsbio.com\/products\/bcl6-monoclonal-antibody-bt-mca3632","provider":"AFSBio Inc.","version":"1.0","type":"link"}