{"product_id":"bdnf-polyclonal-antibody-bs90133","title":"BDNF Polyclonal Antibody-BS90133","description":"\u003cp\u003eBDNF Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90133-50, BS90133-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P23560(Human) P21237(Mouse) P23363(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500\u003cbr\u003e\nICC:1:200\u003cbr\u003e\nIHC:1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Brain-derived neurotrophic factor, also known as BDNF, is a member of the \"neurotrophin\" family of growth factors, which are related to the canonical \"Nerve Growth Factor\", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: BDNF polyclonal antibody detects endogenous levels of BDNF protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 28kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of BDNF on different cell lysates using anti-BDNF antibody at 1\/500 dilution. \u003cbr\u003e\n Positive control: \u003cbr\u003e\n Lane 1: A172 \u003cbr\u003e\n Lane 2: SHG-44 \u003cbr\u003e\n Lane 3: Mouse heart \u003cbr\u003e\n Lane 4: Mouse brain, ICC staining of BNDF in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: BDNF, Abrineurin, ANON2, BDNF, BDNF, Brain Derived Neurotrophic Factor, Brain-derived neurotrophic factor, BULN2, MGC34632, Neurotrophin,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the N-terminal of human BNDF\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979763880115,"sku":"BS90133-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979763912883,"sku":"BS90133-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_458baf6e-147a-4dcd-a68a-7fb6aed3a1d2.jpg?v=1705748892","url":"https:\/\/afsbio.com\/products\/bdnf-polyclonal-antibody-bs90133","provider":"AFSBio Inc.","version":"1.0","type":"link"}