{"product_id":"beta-1-4-gal-t2-polyclonal-antibody-bt-ap09785","title":"Beta-1,4-Gal-T2 Polyclonal Antibody - BT-AP09785","description":"\u003cp\u003eBeta-1,4-Gal-T2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09785-20, BT-AP09785-50, BT-AP09785-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: B4GALT2 (beta-1,4-galactosyltransferase 2) is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: glcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by B4GALT2 synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for B4GALT2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: B4GALT2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: beta-1,4-Gal-T2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 41972\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60909; Mouse: Q9Z2Y2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: B4GALT2; Beta-1; 4-galactosyltransferase 2; Beta-1,4-GalTase 2; Beta4Gal-T2; b4Gal-T2; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosylt\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8704; Mouse: 53418\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240002183347,"sku":"BT-AP09785-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240002216115,"sku":"BT-AP09785-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240002248883,"sku":"BT-AP09785-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a2521b8d-a725-437a-a182-820d2e5af527.png?v=1769401973","url":"https:\/\/afsbio.com\/products\/beta-1-4-gal-t2-polyclonal-antibody-bt-ap09785","provider":"AFSBio Inc.","version":"1.0","type":"link"}