{"product_id":"beta-arrestin-1-6a1-monoclonal-antibody-mb3022","title":"beta Arrestin 1 (6A1) Monoclonal Antibody-MB3022","description":"\u003cp\u003ebeta Arrestin 1 (6A1) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3022-50, MB3022-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49407\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Members of arrestin\/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of betaArrestin 1 in K562 and HelaLysates using betaArrestin 1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG2b\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant human β-Arrestin 1 protein.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42932522483891,"sku":"MB3022-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42932522516659,"sku":"MB3022-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4350e349-3427-47d0-b796-a1a6a3533f5b.jpg?v=1704284448","url":"https:\/\/afsbio.com\/products\/beta-arrestin-1-6a1-monoclonal-antibody-mb3022","provider":"AFSBio Inc.","version":"1.0","type":"link"}