{"product_id":"beta-tubulin-monoclonal-antibody-mb65889","title":"Beta-tubulin Monoclonal Antibody-MB65889","description":"\u003cp\u003eBeta-tubulin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB65889-50, MB65889-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Zebrafish\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/2000 - 1\/5000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and maintenance. Binding of NTN1\/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977).\u003cbr\u003e\nPlays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Beta-tubulin protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Beta-tubulin expression in zebrafish skeletal muscle (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 55 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TUBB4; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence of zebrafish Beta-tubulin. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908742484147,"sku":"MB65889-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908742516915,"sku":"MB65889-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_709e1bae-492d-4638-a310-7edd3a865e6c.jpg?v=1703006531","url":"https:\/\/afsbio.com\/products\/beta-tubulin-monoclonal-antibody-mb65889","provider":"AFSBio Inc.","version":"1.0","type":"link"}