{"product_id":"bex3-polyclonal-antibody-bt-ap14453","title":"BEX3 Polyclonal Antibody - BT-AP14453","description":"\u003cp\u003eBEX3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14453-20, BT-AP14453-50, BT-AP14453-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR\/NGFR.,May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous:Binds transition metals.,PTM:Ubiquitinated. Degraded by the proteasome.,Belongs to the BEX family.,subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.,subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO\/SMAC (By similarity). Binds to the DEATH domain of p75NTR\/NGFR.,tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NGFRAP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Protein BEX3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q00994; Mouse: Q9WTZ9; Rat: Q6PDU5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Protein BEX3;Brain-expressed X-linked protein 3;Nerve growth factor receptor-associated protein 1;Ovarian granulosa cell 13.0 kDa protein HGR74;p75NTR-associated cell death executor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 27018\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239066296499,"sku":"BT-AP14453-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239066329267,"sku":"BT-AP14453-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239066362035,"sku":"BT-AP14453-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c2c7ff53-f152-4964-9cf1-a48bec4794bc.png?v=1769388657","url":"https:\/\/afsbio.com\/products\/bex3-polyclonal-antibody-bt-ap14453","provider":"AFSBio Inc.","version":"1.0","type":"link"}