{"product_id":"bex3-polyclonal-antibody-ra31284","title":"BEX3 Polyclonal Antibody - RA31284","description":"\u003cp\u003eBEX3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA31284-50, RA31284-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: domain:The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR\/NGFR.,function:May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity) . May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous:Binds transition metals.,PTM:Ubiquitinated. Degraded by the proteasome.,similarity:Belongs to the BEX family.,subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.,subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE) . Interacts with DIABLO\/SMAC (By similarity) . Binds to the DEATH domain of p75NTR\/NGFR.,tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 27018\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 12\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q00994\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120428638387,"sku":"RA31284-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120428671155,"sku":"RA31284-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8660f65b-7cfc-46ea-ac2f-a070f7ea920d.png?v=1773365320","url":"https:\/\/afsbio.com\/products\/bex3-polyclonal-antibody-ra31284","provider":"AFSBio Inc.","version":"1.0","type":"link"}