{"product_id":"biotin-anti-human-cd127-il-7ra-antibody-a019d5-e-ab-f1152b","title":"Biotin Anti-Human CD127\/IL-7RA Antibody [A019D5] - E-AB-F1152B","description":"\u003cp\u003eBiotin Anti-Human CD127\/IL-7RA Antibody [A019D5]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F1152B-25, E-AB-F1152B-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD127\/IL-7RA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-7 receptor subunit alpha, IL-7RA, CDw127, CD127, IL-7Rα,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: Biotin\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: A019D5\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P16871\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4\/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09793B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 3575\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"25μg","offer_id":43157152759987,"sku":"E-AB-F1152B-25","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43157152792755,"sku":"E-AB-F1152B-100","price":588.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_66e4cba7-f9c8-4ec0-81ab-efd82b5ba8f7.png?v=1710511656","url":"https:\/\/afsbio.com\/products\/biotin-anti-human-cd127-il-7ra-antibody-a019d5-e-ab-f1152b","provider":"AFSBio Inc.","version":"1.0","type":"link"}