{"product_id":"biotin-anti-mouse-cd120b-tnfr2-antibody-tr75-54-7-e-ab-f1035b","title":"Biotin Anti-Mouse CD120b\/TNFR2 Antibody [TR75-54.7] - E-AB-F1035B","description":"\u003cp\u003eBiotin Anti-Mouse CD120b\/TNFR2 Antibody [TR75-54.7]\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: E-AB-F1035B-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD120b\/TNFR2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor necrosis factor receptor superfamily member 1B, Tnfrsf1b, Tumor necrosis factor receptor 2, TNF-R2, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: Biotin\u003c\/p\u003e\n\n\u003cp\u003eHost: Armenian Hamster\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Armenian Hamster IgG\u003c\/p\u003e\n\n\u003cp\u003eClone No.: TR75-54.7\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P25119\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F09853B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 21938\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43157336752307,"sku":"E-AB-F1035B-100","price":151.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_65015301-04cf-4ea7-a606-ba040866ba33.png?v=1710513653","url":"https:\/\/afsbio.com\/products\/biotin-anti-mouse-cd120b-tnfr2-antibody-tr75-54-7-e-ab-f1035b","provider":"AFSBio Inc.","version":"1.0","type":"link"}