{"product_id":"biotinylated-human-5t4-c-avi-6his-ept158","title":"Biotinylated Human 5T4 (C-Avi-6His) - EPT158","description":"\u003cp\u003eBiotinylated Human 5T4 (C-Avi-6His)\u003c\/p\u003e\n\n\u003cp\u003eSize: 20ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT158-20\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt\/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TPBG; 5T4; 5T4AG; M6P1; WAIF1\u003c\/p\u003e\n\n\u003cp\u003eDescription: Biotinylated Recombinant Human Trophoblast Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a Avi, 6His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q13641\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 38 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 60-90 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eRedissolve: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg\/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211036098739,"sku":"EPT158-20","price":754.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_86c6db02-d09a-4e25-82b8-df4b1c98e9aa.png?v=1767117715","url":"https:\/\/afsbio.com\/products\/biotinylated-human-5t4-c-avi-6his-ept158","provider":"AFSBio Inc.","version":"1.0","type":"link"}