{"product_id":"blk-monoclonal-antibody-bt-mca3177","title":"BLK Monoclonal Antibody - BT-MCA3177","description":"\u003cp\u003eBLK Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3177-50, BT-MCA3177-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BLK\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1E6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BLK\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human BLK expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 58kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P51451\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MODY11, MGC10442, BLK\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 640\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238614261939,"sku":"BT-MCA3177-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238614294707,"sku":"BT-MCA3177-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a7aefa92-2fec-4b33-b7c8-a81bd2983f53.png?v=1769383086","url":"https:\/\/afsbio.com\/products\/blk-monoclonal-antibody-bt-mca3177","provider":"AFSBio Inc.","version":"1.0","type":"link"}