{"product_id":"blk-phospho-tyr501-rabbit-pab-es7144","title":"Blk (phospho Tyr501) rabbit pAb - ES7144","description":"\u003cp\u003eBlk (phospho Tyr501) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7144-50, ES7144-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501. AA range:456-505\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 640\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P51451\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane; Lipid-anchor. Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201931698355,"sku":"ES7144-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201931731123,"sku":"ES7144-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_eac58fc3-10eb-4158-9d53-b5b2fc2a6d4d.png?v=1767118250","url":"https:\/\/afsbio.com\/products\/blk-phospho-tyr501-rabbit-pab-es7144","provider":"AFSBio Inc.","version":"1.0","type":"link"}