{"product_id":"blnk-monoclonal-antibody-bt-mca3392","title":"BLNK Monoclonal Antibody - BT-MCA3392","description":"\u003cp\u003eBLNK Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3392-50, BT-MCA3392-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: BLNK\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5G9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BLNK\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human BLNK expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 68kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q8WV28\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AGM4, BASH, LY57, SLP65, BLNK-S, SLP-65, MGC111051\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 29760\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238600171699,"sku":"BT-MCA3392-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238600204467,"sku":"BT-MCA3392-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7eae3b67-a51c-4024-8179-112aa58a6140.png?v=1769382948","url":"https:\/\/afsbio.com\/products\/blnk-monoclonal-antibody-bt-mca3392","provider":"AFSBio Inc.","version":"1.0","type":"link"}