{"product_id":"bmal1-phospho-ser42-rabbit-polyclonal-antibody-bt-ap00807","title":"BMAL1 (Phospho-Ser42) Rabbit Polyclonal Antibody - BT-AP00807","description":"\u003cp\u003eBMAL1 (Phospho-Ser42) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00807-20, BT-AP00807-50, BT-AP00807-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1| PER2| PER3) and Cryptochrome (CRY1| CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK\/ARNTL complexes. Defects in this gene have been linked to infertility| problems with gluconeogenesis and lipogenesis| and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Epigenetics and nuclear signaling; Metabolism; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ARNTL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: BMAL1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O00327; Mouse: Q9WTL8; Rat: Q9EPW1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BMAL1;Ser42; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 406; Mouse: 11865; Rat: 29657\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238972580019,"sku":"BT-AP00807-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238972612787,"sku":"BT-AP00807-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238972645555,"sku":"BT-AP00807-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a9b6a174-6d9c-4f6d-b250-df335f23fe7f.png?v=1769387399","url":"https:\/\/afsbio.com\/products\/bmal1-phospho-ser42-rabbit-polyclonal-antibody-bt-ap00807","provider":"AFSBio Inc.","version":"1.0","type":"link"}